Liverpool host Manchester City in the Premier League at Anfield on Saturday, October 10, 2026, kickoff 14:00 UTC. ESPN's head-to-head shows Manchester City winning all three 2025-26 meetings, including 3-0 at Anfield in the league and 4-0 at Anfield in the FA Cup quarterfinals.

Arsenal host Everton in the Premier League at the Emirates Stadium on Saturday, October 24, 2026, kickoff 14:00 UTC. ESPN's head-to-head shows Arsenal won both 2025-26 league meetings (2-0 and 1-0), with a 1-1 draw in 2024-25.

Aston Villa host Manchester City in the Premier League at Villa Park on Saturday, October 24, 2026, kickoff 14:00 UTC. ESPN's head-to-head shows the sides split the 2025-26 league meetings: Villa won 2-1 on May 24, 2026, and City won 1-0 earlier in the season.

Liverpool host Arsenal in the Premier League at Anfield on Saturday, October 31, 2026, kickoff 15:00 UTC. ESPN's head-to-head shows Arsenal winning 1-0 in their most recent league visit to Anfield, in 2025-26.

Chelsea host Manchester United in the Premier League at Stamford Bridge on Saturday, October 31, 2026, kickoff 15:00 UTC. ESPN's head-to-head shows United winning 2-1 at Stamford Bridge in 2025-26, while Chelsea won 2-0 at Old Trafford the same season.

Liverpool host Manchester United in the Premier League at Anfield on Saturday, November 21, 2026, kickoff 15:00 UTC. ESPN's head-to-head shows United winning both 2025-26 league meetings, 3-2 and 2-1, after Liverpool went unbeaten against them in 2024-25 with a 3-0 win and a 2-2 draw.

Arsenal host Manchester City in the Premier League at Emirates Stadium on Saturday, November 28, 2026, kickoff 15:00 UTC. ESPN's head-to-head shows Arsenal winning the most recent league meeting, away at Manchester City in 2025-26.

Chelsea host Liverpool in the Premier League at Stamford Bridge on Saturday, December 5, 2026, kickoff 15:00 UTC. ESPN's head-to-head shows the sides' most recent meeting, in May of the 2025-26 season, ended in a 1-1 draw.

Manchester City host Chelsea in the Premier League at the Etihad Stadium on Saturday, December 12, 2026, kickoff 15:00 UTC. ESPN's head-to-head shows City beat Chelsea 1-0 in the 2025-26 FA Cup final.

Manchester United host Newcastle United in the Premier League at Old Trafford on Wednesday, January 6, 2027, kickoff 20:00 UTC. ESPN's head-to-head shows Newcastle winning both 2025-26 league meetings, 2-1 and 1-0, after the sides split in 2024-25 with a 4-1 Newcastle win and a 2-0 United win.

Manchester United host Liverpool in the Premier League at Old Trafford on Saturday, January 23, 2027, kickoff 15:00 UTC. It is the return fixture to the sides' November 21 meeting at Anfield earlier in the season.

Manchester United host Chelsea in the Premier League at Old Trafford on Saturday, February 6, 2027, kickoff 15:00 UTC. It is the return fixture to the sides' October 31, 2026 meeting at Stamford Bridge.

Newcastle United host Chelsea in the Premier League at St. James' Park on Wednesday, February 10, 2027, kickoff 20:00 UTC. ESPN's head-to-head shows one of the sides' 2025-26 league meetings ended in a 2-2 draw.

Manchester United host Arsenal in the Premier League at Old Trafford on Saturday, February 27, 2027, kickoff 15:00 UTC.

Manchester City host Manchester United in the Premier League Manchester derby at the Etihad Stadium on Saturday, March 20, 2027, kickoff 15:00 UTC, the return leg of the September 13 derby at Old Trafford. ESPN's head-to-head shows United winning both 2025-26 league meetings, 2-0 and 3-0.

Manchester United host Crystal Palace in the Premier League at Old Trafford on Saturday, April 24, 2027, kickoff 14:00 UTC. ESPN's head-to-head shows the sides splitting the 2025-26 league meetings, each winning 2-1.

Chelsea host Manchester City in the Premier League at Stamford Bridge on Saturday, April 24, 2027, kickoff 14:00 UTC. ESPN's head-to-head shows one of the sides' 2025-26 league meetings ended in a 1-1 draw.

Liverpool host Chelsea in the Premier League at Anfield on Saturday, May 1, 2027, kickoff 14:00 UTC. ESPN's head-to-head shows the sides' most recent meeting, in May of the 2025-26 season, ended in a 1-1 draw.

Tottenham Hotspur host Chelsea in a London derby in the Premier League at Tottenham Hotspur Stadium on Saturday, May 8, 2027, kickoff 14:00 UTC, one week after Chelsea's trip to Anfield.

Chelsea host Everton in the Premier League at Stamford Bridge on Saturday, May 15, 2027, kickoff 14:00 UTC. ESPN's head-to-head shows one of the sides' 2024-25 league meetings ended 0-0.

Tottenham Hotspur host Manchester United in the Premier League at Tottenham Hotspur Stadium in London on Sunday, May 23, 2027, kickoff 14:00 UTC. It is the last Manchester United fixture on the agenda for the 2026-27 season.